peptide bond

Describe peptide bond formation and its structure in great detail .

请详细描述胜肽键的形成与其结构。

Can you deduce other structure formations based on the peptide bond structure ?

你可以基于肽键结构推导出其它结构吗？

Individual proteases are highly specific in the type of peptide bond they hydrolyze .

单个的蛋白酶对他们水解的肽键类型具高度特异性。

There are two general methods for the formation of peptide bond , i.e. amino activation or carboxylic group activation .

形成肽键的基本方法，可以活化氨基也可以活化羧基，但是迄今为止普遍使用的都是活化羧基的方法。

All kinds of proteins and polypeptides are built by amino acids residues through peptide bond .

这些种类繁多的蛋白质和多肽，从化学结构上看，都是由氨基酸残基通过酰胺键（肽键）连接而成的。

The protein is a kind of biological macromolecules constructed by 20 types of amino acid with peptide bond .

蛋白质是一种生物大分子，是由20种氨基酸以肽键连接成肽链，在空间卷曲折叠成为特定的三维空间结构。

The peptide bond has substantial rigid double-bond character and affects properties of proteins by limiting available information .

肽键实质上具有稳定的双键特性，并且通过限制有效信息来影响蛋白质的特性。

H3 N-tail modifications also include cleavage of its peptide bond by amide hydrolysis .

H3氨基端的修饰同样也包括其残基的肽键被水解而切割。

Trans-formanilide is one of the simplest aromatic amides and provides a model of the peptide bond .

化合物trans-formanilide是研究肽键的常用模型，又是最简单芳香类酰胺分子。

Studies on the Proton Transfer Mechanisms and Relevant Properties of Glycinamide and Its Derivatives Associated with the Cis Peptide Bond Units

与顺式肽键单元相关的甘氨酰胺及其衍生物的质子转移机制及相关性质研究

, which makes it easy for the nucleophile ( solvent water ) to attack and cleave the peptide bond .

配位之后，羰基碳所带的正电荷增加了28.3%，使它极易受到亲核试剂（溶剂水）的进攻而使肽键发生断裂，这为钯？

When the water content is as low as 20 % , the form of - S-S - bond is less . The peptide bond may the more important factor .

当水分较低时（20%），二硫键结合较少，可能肽键结合是主要的。

In this work , a series of theoretical methods were employed to investigate the reaction mechanisms of ribosomal peptide bond formation catalyzed by peptidyl transferase .

本文运用一系列的理论化学方法研究了肽酰转移酶催化肽键形成的机理。

For the studies described in the second chapter , reaction pathways and free energy barriers for the model reaction of the peptide bond synthesis were studied by performing Ab initio calculation .

第二章中我们运用量子化学从头算的方法研究了由肽酰转移酶催化肽键形成的模型反应，并估算了各个反应的自由能垒。

In the last chapter , molecular dynamics simulations and quantum mechanical were performed to study the other possible mechanism of ribosomal peptide bond formation catalyzed by peptidyl transferase .

第四章中我们运用了量子化学从头算和分子动力学模拟的方法研究了肽酰转移酶催化的其它反应途径。

The hydrophilic side chains and peptide bond enhance the negative values of the transfer enthalpy . In contrast , the hydrophobic side chain has positive contributions to the transfer enthalpy .

氨基酸的亲水侧链和肽的肽键对迁移焓有负贡献，氨基酸疏水侧链对迁移焓有正贡献。

The dataset maybe was important to those researches such as the structure of X - Pro peptide bond , the relation between amino acid sequence and structure , peptide chain folding kinetics .

此数据集对于进一步研究顺反X-Pro肽键的结构、与氨基酸序列之间的关系，以及肽链折叠动力学具有重要作用。

The main interactions come from dehydration and ion / hydrophilic-ion interaction between the zwitterions of amino acid or peptide bond of peptide and the head group of surfactant .

主要作用为吸热的去水化作用和氨基酸分子的两性离子/肽分子的肽键与表面活性剂分子的离子头基间放热的离子/亲水&离子相互作用。

CasPase-3 is a group of structure related cysteine protease that existed in the cytoplasm Sol , in which an important common ground specific is disconnect between aspartate residue peptide bond .

CasPase是近年来发现的一组存在于胞质溶胶中的结构上相关的半胱氨酸蛋白酶，它们的一个重要共同点是特异地断开天冬氨酸残基后的肽键。

The thesis consists of three chapters , including ( 1 ) basic theory and computational methods . ( 1 ) Theoretical study on mechanism of ribosomal peptide bond formation catalyzed by peptidyl transferase .

全文由四章组成：（1）理论基础和计算方法（2）肽酰转移酶催化机理的理论研究；

It can directly act on the fibrinogen , and hydrolyzes 4 Arg-Gly peptide bond of the fibrinogen , which makes fibrinogen become to fibrin for congealing the blood .

它能直接作用于血中的纤维蛋白原，水解血液中纤维蛋白原的4个Arg-Gly肽键，产生不溶性的纤维蛋白，使血液变成凝胶而发生凝固。

The amide of the peptide bond in the Dipeptide inhibitors which included aromatic series amino acid showed trans configuration with the hydroxide of the benzene ring . There were seven bonds between them .

含芳香族氨基酸的二肽抑制剂中的肽键的氨基和苯环部分羟基端呈反式构型，它们相隔7个键位。

Protease acting on wool fiber , can catalyze the hydrolysis of the peptide bond , is considered to be the most promising process which can replace the traditional chlorination-resin anti-shrinkage finishing process .

蛋白酶作用于羊毛纤维，能催化肽键水解，被认为是替代传统的氯化-树脂防毡缩整理工艺的最具潜力的方法。

Intein able to catalyze self-splicing from the precursor protein and the exteins were ligated with a peptide bond . This post-translation process was termed protein splicing .

在宿主蛋白质的成熟过程中，蛋白质内含子可以催化自身从蛋白质前体中剪切下来，同时将两侧的外显子以肽键连接，这种蛋白质翻译后的成熟过程称为蛋白质剪接（proteinsplicing）。

In the third chapter , first-principles electronic structure calculations were performer to study the reaction mechanisms of ribosomal peptide bond formation catalyzed by 9-methyl Guanine or 1-methyl Uracil instead of Adenine .

第三章中我们运用量子化学从头算的方法研究，利用9-甲基鸟嘌呤和1-甲基尿嘧啶来分别替代鸟嘌呤核苷和尿嘧啶核苷进行分子突变后的反应机理的模型化学研究。

With the increase of hydrophile and the number of peptide bond , the concentration range of hydration decreases . The contributions of the hydrophobic side chains of the amino acids to the transfer enthalpy are positive .

随表面活性剂头基亲水性的增强和肽分子中肽键的增多，去水化作用范围减小；随氨基酸疏水侧链体积的增大，对迁移焓的正贡献增强。

IR analysis shows that the product contains peptide bond , lactone bond , and aliphatic chain GC MS analysis indicates that hydrophobic moiety contains β methyl C 14 fatty acid and β hydroxyl C 18 fatty acid .

IR分析表明该物质含有肽键、内脂键及脂肪族侧链等官能团；GC-MS和PC分析表明，其疏水基半分子为β-甲基十四碳脂肪酸及β-羟基十八碳脂肪酸；

Trypsin is a kind of main alkaline proteolytic enzymes in alimentary canal . It belongs to the family of serine proteinase , and specially hydrolyzes the peptide bond formed by Lysine or Arginine .

胰蛋白酶（Trypsin）是动物消化道中一种主要的蛋白水解酶，属于丝氨酸蛋白酶家族，能专一性水解赖氨酸或精氨酸羧基形成的肽键。

Phosphate esters and anhydrides play important roles in the biosynthesis of proteins , they act as the activators and carriers of amino acids in the biochemical reactions , and go away as the leaving groups after the formation of peptide bond .

磷酸酯及其酸酐在蛋白质的生物合成中起着十分重要的作用，它们充当了氨基酸的活化试剂和运输载体，当肽键形成后又作为离去基团离去。

A new tetraphenyl porphyrin anthraquinone bridged by peptide bond , as a compound for studying photo induced electron transfer , was synthesized recently . The photo induced intramolecular electron transfer reactions of this compound were studied by Time Correlated Single Photon Counting method in different solvents .

首次合成了肽键桥连的四苯卟啉－蒽醌（TPP－AQ）化合物，以此作为研究光合成电子传递的模型化合物，用时间相关单光子荧光技术研究了该化合物在不同溶剂中分子内的电子转移。